SCHEMBL6652604

SCHEMBL6652604

CC(C)OC(Cc1cccc(C(C)(O)C#C[Si](C)(C)C)c1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.43
PPARA Q07869 20/20 0.43
PPARD Q03181 12/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4341220 0.89 MAPK1 (0.35) PPARGPPARAPPARD
SCHEMBL4329800 0.81 PPARA (0.42) PPARGPPARAPPARD
SCHEMBL4338932 0.81 PPARA (0.45) PPARGPPARAPPARD
SCHEMBL4332660 0.81 PPARA (0.47) PPARGPPARAPPARD
SCHEMBL4337056 0.80 PPARA (0.42) PPARGPPARAPPARD
SCHEMBL4341762 0.79 PPARA (0.42) PPARGPPARAPPARD
SCHEMBL4335668 0.79 PPARG (0.42) PPARGPPARAPPARD
SCHEMBL13819769 0.76 PPARG (0.55) PPARGPPARAPPARD
SCHEMBL13819285 0.76 PPARG (0.46) PPARGPPARAPPARD
SCHEMBL13819723 0.76 PPARA (0.46) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1380562-A1 CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF Eisai Co., Ltd. (JP) 2004-01-14 EP disclosed