Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.54 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.54 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.54 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872622 | 1.00 | ABCB1 (0.54) | ABCB1KCNE1KCNQ1KCNH2SCN5A | |
| SCHEMBL4869347 | 0.92 | ABCB1 (0.51) | ABCB1KCNE1KCNQ1KCNH2SCN5A | |
| SCHEMBL4871411 | 0.92 | ABCB1 (0.54) | ABCB1KCNE1KCNQ1KCNH2SCN5A | |
| SCHEMBL6619823 | 0.92 | ABCB1 (0.51) | ABCB1KCNE1KCNQ1KCNH2SCN5A | |
| SCHEMBL4875614 | 0.92 | ABCB1 (0.54) | ABCB1KCNE1KCNQ1KCNH2SCN5A | |
| SCHEMBL4869216 | 0.92 | ABCB1 (0.54) | ABCB1KCNE1KCNQ1KCNH2SCN5A | |
| SCHEMBL4870072 | 0.92 | ABCB1 (0.53) | ABCB1KCNE1KCNQ1KCNH2SCN5A | |
| SCHEMBL4873985 | 0.91 | ABCB1 (0.54) | ABCB1KCNE1KCNQ1KCNH2SCN5A | |
| SCHEMBL4874195 | 0.89 | ABCB1 (0.52) | ABCB1KCNE1KCNQ1KCNH2SCN5A | |
| SCHEMBL4869218 | 0.89 | ABCB1 (0.50) | ABCB1KCNE1KCNQ1KCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086076-B1 | SULFONAMIDE INHIBITORS OF ASPARTYL PROTEASE | VERTEX PHARMA (US) | 2004-12-22 | — | — | EP | disclosed |