Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.88 |
| ▸ | LCK | P06239 | 1/20 | 0.88 |
| ▸ | FYN | P06241 | 1/20 | 0.88 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10641112 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL9841862 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL27534860 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL36402 | 1.00 | — | — | |
| Acetic Acid SCHEMBL21647264 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL11258467 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL11372553 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL4273550 | 0.94 | — | — | |
| Acetic Acid SCHEMBL11332769 | 0.94 | — | — | |
| Acetic Acid SCHEMBL9270196 | 0.94 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107290446-B | A kind of molecular weight or molecular weight distribution detection method of alkaline polymer | 山东圣泉新材料股份有限公司 | 2019-10-01 | — | — | CN | disclosed |
| US-10023760-B2 | Semicarbazide composition, method for producing semicarbazide composition, aqueous polymer composition and composite | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2018-07-17 | — | — | US | disclosed |
| CN-104812735-B | Semicarbazide composition, method for producing semicarbazide composition, aqueous resin composition, and composite | 旭化成株式会社 | 2017-03-22 | — | — | CN | disclosed |
| CN-105579426-A | Production of partially refined waste glycerol | REG LIFE SCIENCES LLC | 2016-05-11 | — | — | CN | disclosed |
| US-20150291831-A1 | SEMICARBAZIDE COMPOSITION, METHOD FOR PRODUCING SEMICARBAZIDE COMPOSITION, AQUEOUS POLYMER COMPOSITION AND COMPOSITE | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-10-15 | — | — | US | disclosed |
| EP-2921474-A1 | SEMICARBAZIDE COMPOSITION, METHOD FOR PRODUCING SEMICARBAZIDE COMPOSITION, AQUEOUS RESIN COMPOSITION AND COMPOSITE | Asahi Kasei Chemicals Corporation (JP) | 2015-09-23 | — | — | EP | disclosed |
| CN-104812735-A | Semicarbazide composition, method for producing semicarbazide composition, aqueous resin composition, and composite | ASAHI KASEI CHEMICALS CORP | 2015-07-29 | — | — | CN | disclosed |
| CN-104570668-A | Image forming apparatus and image forming method | FUJI XEROX CO LTD | 2015-04-29 | — | — | CN | disclosed |
| EP-1140108-B1 | METHOD AND COMPOSITION FOR TREATMENT OF FEMALE SEXUAL DYSFUNCTION | SYNPHORA AB (SE) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291831-A1 | SEMICARBAZIDE COMPOSITION, METHOD FOR PRODUCING SEMICARBAZIDE COMPOSITION, AQUEOUS POLYMER COMPOSITION AND COMPOSITE | C9, C5, BRD2 | FFAR3 1500/4885LCK 4845/4885FYN 4811/4885 |
| US-10023760-B2 | Semicarbazide composition, method for producing semicarbazide composition, aqueous polymer composition and composite | C9, C5, BRD2 | FFAR3 1500/4885LCK 4845/4885FYN 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.