⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13730288 | 0.97 | — | — | |
| SCHEMBL9761067 | 0.67 | — | — | |
| SCHEMBL7423144 | 0.67 | — | — | |
| SCHEMBL3813633 | 0.67 | — | — | |
| SCHEMBL7265390 | 0.67 | — | — | |
| SCHEMBL3815061 | 0.64 | — | — | |
| Lithium Ion SCHEMBL8975741 | 0.63 | — | — | |
| SCHEMBL11669627 | 0.63 | — | — | |
| SCHEMBL7266811 | 0.62 | — | — | |
| SCHEMBL7266255 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8059654-A | — | — | None | — | — | JP | disclosed |
| JP-52083672-A | — | — | None | — | — | JP | disclosed |
| EP-3094333-B1 | NO-RELEASING NITROOXY-CHROMENE CONJUGATES | EUCLISES PHARMACEUTICALS INC (US) | 2020-10-14 | — | — | EP | disclosed |
| EP-3351543-A1 | 1-(QUINOLIN-4-YL)-3-(6-(TRIFLUOROMETHYL)-PYRIDIN-2-YL)UREA AND 1-(QUINOLIN-4-YL)-3-(6-(TRIFLUOROMETHYL)-PYRAZINE-2-YL)UREA DERIVATIVES AS GLYCOGEN SYNTHASE KINASE 3 (GSK-3) INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-07-25 | — | — | EP | disclosed |
| EP-1196383-B1 | PROCESS FOR PREPARING AMLODIPINE BENZENESULPHONATE | RICHTER GEDEON VEGYESZET (HU) | 2004-12-01 | — | — | EP | disclosed |
| US-6596874-B1 | Salt formation by reaction using benzenesulfonic acid | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2003-07-22 | — | — | US | disclosed |
| EP-1196383-A1 | PROCESS FOR PREPARING AMLODIPINE BENZENESULPHONATE | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001002360-A1 | PROCESS FOR PREPARING AMLODIPINE BENZENESULPHONATE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2001-01-11 | — | — | WO | disclosed |
| US-5652251-A | 6-amino-1,4-dihydropyridine compounds as medicaments for treatment of the central nervous system, and processes for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | disclosed |
| EP-0515940-B1 | New 2-amino-5-cyano-1,4-dihydropyridines, process for their preparation and use in pharmaceutical compositions | BAYER AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| US-3919246-A | Process for preparing 2-amino-1,4-dihydropyridine derivates | BAYER AG | 1975-11-11 | — | — | US | disclosed |
| US-3919246-A | Process for preparing 2-amino-1,4-dihydropyridine derivates | BAYER AG | 1975-11-11 | — | — | US | disclosed |
| US-3917622-A | 2-Amino-1,4-dihydropyridine derivatives | BAYER AG | 1975-11-04 | — | — | US | disclosed |
| US-3917622-A | 2-Amino-1,4-dihydropyridine derivatives | BAYER AG | 1975-11-04 | — | — | US | disclosed |
| US-3911123-A | Pharmaceutical compositions utilizing 2-amino-1,4-dihydropyridine derivatives and method of effecting coronary vessel dilation and treating hypertension in humans and animals utilizing said compounds | BAYER AG | 1975-10-07 | — | — | US | disclosed |
| US-3911123-A | Pharmaceutical compositions utilizing 2-amino-1,4-dihydropyridine derivatives and method of effecting coronary vessel dilation and treating hypertension in humans and animals utilizing said compounds | BAYER AG | 1975-10-07 | — | — | US | disclosed |
| US-3867393-A | 2-Amino-1,4-dihydropyridine derivatives | MEYER HORST | 1975-02-18 | — | — | US | disclosed |
| US-3867393-A | 2-Amino-1,4-dihydropyridine derivatives | MEYER HORST | 1975-02-18 | — | — | US | disclosed |
| US-3862162-A | CERTAIN-2-AMINO-1,4-DIHYDRO-4-PHENYL-6-LOWER ALKYL (OR PHENYL)-3-PYRIDINECARBOXYLATES | BAYER AG | 1975-01-21 | — | — | US | disclosed |
| US-3857849-A | 2-AMINO-1,4-DIHYDROPYRIDINE DERIVATIVES | BAYER AG | 1974-12-31 | — | — | US | disclosed |