SCHEMBL6653768

SCHEMBL6653768

CCc1cc2c(C(=O)O)cccc2c(CC)c1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.43
NR4A2 P43354 1/20 0.43
NR4A3 Q92570 1/20 0.43
CLCN2 P51788 1/20 0.41
CDC25B P30305 1/20 0.39
ME2 P23368 1/20 0.39
ME1 P48163 1/20 0.39
ME3 Q16798 1/20 0.39
BCL2 P10415 1/20 0.39
PTPN1 P18031 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38
HMGB1 P09429 1/20 0.37
CXCL12 P48061 1/20 0.37
FOLH1 Q04609 1/20 0.37
FABP4 P15090 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
POLB P06746 2/20 0.36
PRNP P04156 1/20 0.36
KDM4E B2RXH2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6651914 0.84 PTPN1 (0.44) NR4A1NR4A2NR4A3PTPN1FOLH1
SCHEMBL6650822 0.81 BID (0.45) KDM4EHSD17B10DHODHALOX15
SCHEMBL8853214 0.77 KDM4E (0.47) NR4A3POLBKDM4EALDH1A1MEN1
SCHEMBL9231673 0.75 CLCN2 (0.41) NR4A1NR4A2NR4A3CLCN2ME2
SCHEMBL27845391 0.74 KDM4E (0.44) POLBKDM4EALDH1A1MEN1CYP1A2
SCHEMBL31401652 0.74 NR4A1 (0.53) NR4A1NR4A2NR4A3CDC25BPTPN1
SCHEMBL2185918 0.74 NR4A1 (0.53) NR4A1NR4A2NR4A3CDC25BPTPN1
SCHEMBL28845360 0.74 FOLH1 (0.42) CLCN2BCL2MRGPRX4FOLH1POLB
SCHEMBL578127 0.74 CLCN2 (0.56) NR4A1NR4A2NR4A3CLCN2MRGPRX4
SCHEMBL32665389 0.74 NR4A1 (0.57) NR4A1NR4A2NR4A3CDC25BPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1424414-A1 Manufacturing method of polyester fiber having improved light fastness NAN YA PLASTICS CORPORATION (TW) 2004-06-02 EP disclosed
US-6620362-B1 Copolymerizing diol and naphthalenedicarboxylic acid NAN YA PLASTICS CORPORATION (TW) 2003-09-16 US disclosed