SCHEMBL6654514

SCHEMBL6654514

C=C(C)C(=O)OC(CC)C(C)O[SiH](CC)CC

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
THRB P10828 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9741483 0.85 TSHR (0.38) TSHRTHRBALDH1A1
SCHEMBL4401548 0.78 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL22231283 0.77 TSHR (0.45) TSHRTHRBALDH1A1
SCHEMBL22231053 0.75 TSHR (0.44) TSHRTHRBALDH1A1
SCHEMBL16328375 0.75 TSHR (0.38) TSHRTHRBALDH1A1
SCHEMBL27808211 0.75 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL23494182 0.74 TSHR (0.42) TSHRTHRBALDH1A1
SCHEMBL22230992 0.74 TSHR (0.42) TSHRTHRBALDH1A1
SCHEMBL22231110 0.73 TSHR (0.41) TSHRTHRBALDH1A1
SCHEMBL27858353 0.73 TSHR (0.41) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1394217-A2 Polymeric compositions useful in plastic resins ROHM AND HAAS COMPANY (US) 2004-03-03 EP disclosed
EP-1394209-A1 Polymeric compositions useful in plastic resins ROHM AND HAAS COMPANY (US) 2004-03-03 EP disclosed
EP-0983318-A1 CHLORINATED POLYVINYL CHLORIDE COMPOUND HAVING EXCELLENT PHYSICAL, CHEMICAL RESISTANCE AND PROCESSING PROPERTIES THE B.F. GOODRICH COMPANY (US) 2000-03-08 EP disclosed
WO-1998053005-A1 CHLORINATED POLYVINYL CHLORIDE COMPOUND HAVING EXCELLENT PHYSICAL, CHEMICAL RESISTANCE AND PROCESSING PROPERTIES THE B.F. GOODRICH COMPANY (US) 1998-11-26 WO disclosed
EP-0326041-A1 Vinyl chloride resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-08-02 EP disclosed