Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1GSK3AGSK3BHRH1HRH2HTR7IDH1IDH2IMPA1IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.33 |
| ▸ | CPT2 | P23786 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL1684057 | 0.98 | CA4 (0.73) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL29276644 | 0.95 | CA4 (0.70) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL30043113 | 0.95 | CA4 (0.70) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL27590360 | 0.95 | CA4 (0.77) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL11132767 | 0.95 | CA4 (0.70) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL7946479 | 0.95 | CA4 (0.70) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL27487044 | 0.95 | CA4 (0.77) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL2341328 | 0.95 | CA4 (0.70) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL7946484 | 0.95 | CA4 (0.70) | CA4ALDH1A1HMGCRCHRM1TBXA2R | |
| Citric Acid SCHEMBL28066177 | 0.95 | CA4 (0.70) | CA4ALDH1A1HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191431-B1 | MICRONUTRIENT FERTILIZER | SUN CHEMICAL CORP (US) | 2023-03-08 | — | — | EP | claimed |
| CN-109762671-B | Composite stabilizer for stabilizing protease in laundry detergent | 江南大学 | 2021-03-30 | — | — | CN | claimed |
| CN-111635832-A | Efficient clothes detergent and preparation method thereof | 华洁化工(新丰)有限公司 | 2020-09-08 | — | — | CN | claimed |
| US-10407353-B2 | Micronutrient fertilizer | SUN CHEMICAL CORPORATION (US) | 2019-09-10 | — | — | US | claimed |
| CN-109762671-A | It is a kind of for stablizing the compound stabilizer of protease in liquid detergent | 江南大学 | 2019-05-17 | — | — | CN | claimed |
| US-20170283334-A1 | MICRONUTRIENT FERTILIZER | SUN CHEMICAL CORPORATION (US) | 2017-10-05 | — | — | US | claimed |
| EP-3191431-A1 | MICRONUTRIENT FERTILIZER | Sun Chemical Corporation (US) | 2017-07-19 | — | — | EP | claimed |
| WO-2016040564-A1 | MICRONUTRIENT FERTILIZER | SUN CHEMICAL CORPORATION (US) | 2016-03-17 | — | — | WO | claimed |
| CN-115109771-B | Composite neutral protease stabilizer and application thereof | 河北省微生物研究所有限公司 | 2025-01-28 | — | — | CN | disclosed |
| EP-3191431-B1 | MICRONUTRIENT FERTILIZER | SUN CHEMICAL CORP (US) | 2023-03-08 | — | — | EP | disclosed |
| CN-115109771-A | Composite neutral protease stabilizer and application thereof | 河北省微生物研究所有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-109762671-B | Composite stabilizer for stabilizing protease in laundry detergent | 江南大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-109762671-B | Composite stabilizer for stabilizing protease in laundry detergent | 江南大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-111635832-A | Efficient clothes detergent and preparation method thereof | 华洁化工(新丰)有限公司 | 2020-09-08 | — | — | CN | disclosed |
| CN-1556678-A | Process for the fortification of a fruit based food product with calcium | 普拉克生化公司 | 2004-12-22 | — | — | CN | disclosed |
| US-20040161496-A1 | Process for the fortification of a fruit-based food product with calcium | PURAC BIOCHEM B.V. (NL) | 2004-08-19 | — | — | US | disclosed |
| EP-1429630-A1 | PROCESS FOR THE FORTIFICATION OF A FRUIT BASED FOOD PRODUCT WITH CALCIUM | Purac Biochem B.V. (NL) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003024250-A1 | PROCESS FOR THE FORTIFICATION OF A FRUIT BASED FOOD PRODUCT WITH CALCIUM | PURAC BIOCHEM B.V. (NL) | 2003-03-27 | — | — | WO | disclosed |
| US-20030059499-A1 | Process for the fortification of a fruit based food product with calcium | PURAC BIOCHEM B.V. (NL) | 2003-03-27 | — | — | US | disclosed |
| EP-1295536-A1 | Process for the fortification of a fruit based food product with calcium | Purac Biochem B.V. (NL) | 2003-03-26 | — | — | EP | disclosed |