Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903928 | 0.90 | ELANE (0.36) | NPC1RAB9AFABP4FABP5GAA | |
| SCHEMBL6657678 | 0.87 | EGLN1 (0.39) | NPC1RAB9AFABP4FABP5AKR1C3 | |
| SCHEMBL6766837 | 0.86 | MAPK1 (0.38) | RAB9AFABP4FABP5GAAMAPT | |
| SCHEMBL6684234 | 0.81 | MAPT (0.35) | NPC1RAB9AFABP4FABP5GAA | |
| SCHEMBL6858357 | 0.80 | PDE5A (0.42) | ALDH1A1 | |
| SCHEMBL6638476 | 0.76 | HSD17B10 (0.40) | SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6764615 | 0.75 | PDE10A (0.40) | SMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL6743866 | 0.74 | MAPK1 (0.38) | NPC1RAB9AFABP4FABP5SMN1; SMN2 | |
| SCHEMBL6859891 | 0.74 | KMT2A (0.40) | NPC1RAB9AGAAMAPTALDH1A1 | |
| SCHEMBL6761170 | 0.74 | GAA (0.43) | GAANPSR1MAPTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280792-B1 | METHOD FOR PRODUCING BENZO ANNELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2004-07-14 | — | — | EP | claimed |