Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 1.00 |
| ▸ | MAPK13 | O15264 | 15/20 | 1.00 |
| ▸ | MAPK12 | P53778 | 15/20 | 1.00 |
| ▸ | MAPK11 | Q15759 | 15/20 | 1.00 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652639 | 0.92 | MAPK14 (0.85) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL27529702 | 0.87 | MAPK14 (0.78) | MAPK14MAPK13MAPK12MAPK11GRM4 | |
| SCHEMBL6659531 | 0.87 | MAPK14 (0.77) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL5989531 | 0.86 | MAPK14 (0.78) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL7191939 | 0.85 | MAPK14 (0.74) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL27480922 | 0.85 | MAPK13 (0.74) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL7196435 | 0.84 | MAPK14 (0.76) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL27482085 | 0.84 | MAPK13 (0.72) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL6655143 | 0.83 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL7199535 | 0.83 | MAPK14 (0.74) | MAPK14MAPK13MAPK12MAPK11GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013086002-A1 | COMPOSITIONS, PROCESS OF PREPARATION OF SAID COMPOSITIONS AND METHOD OF TREATING CANCER | CELLWORKS RESEARCH INDIA PRIVATE LIMITED (IN) | 2013-06-13 | — | — | WO | disclosed |
| WO-2013086002-A1 | COMPOSITIONS, PROCESS OF PREPARATION OF SAID COMPOSITIONS AND METHOD OF TREATING CANCER | CELLWORKS RESEARCH INDIA PRIVATE LIMITED (IN) | 2013-06-13 | — | — | WO | disclosed |
| CN-1188388-C | Aminobenzophenones as inhibitors of interleukin and TNF | LEO PHARM PROD LTD (DK) | 2005-02-09 | — | — | CN | disclosed |
| EP-0966424-B1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMA AS (DK) | 2004-06-23 | — | — | EP | disclosed |
| US-6313174-B1 | FOR THERAPY AND PROPHYLAXIS OF ASTHMA, ALLERGY, RHEUMATOID ARTHRITIS, SPONDYLOARTHRITIS, GOUT, ATHEROSCLEROSIS, CHRONIC INFLAMMATORY BOWEL DISEASE, PROLIFERATIVE AND INFLAMMATORY SKIN DISORDERS | Leo Pharmaceutical Products Ltd.A/S/ (Løvens kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-11-06 | — | — | US | disclosed |