Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15326142 | 0.86 | MEN1 (0.44) | MEN1KMT2AADORA3NPC1RAB9A | |
| SCHEMBL6657927 | 0.85 | MEN1 (0.49) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL6657931 | 0.85 | MEN1 (0.49) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL6657925 | 0.85 | MEN1 (0.49) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL14671407 | 0.81 | MEN1 (0.51) | MEN1KMT2AL3MBTL1KDM4C | |
| SCHEMBL6903532 | 0.78 | MAPT (0.48) | MEN1KMT2AADORA3KDM4CALDH1A1 | |
| SCHEMBL14671433 | 0.77 | MEN1 (0.45) | MEN1KMT2AL3MBTL1KDM4C | |
| SCHEMBL8003850 | 0.77 | MEN1 (0.48) | MEN1KMT2AL3MBTL1RAB9ACYP1A2 | |
| SCHEMBL16001837 | 0.76 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL14671441 | 0.76 | MEN1 (0.44) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1110943-B1 | 6-FLUOROBICYCLO 3. 1.0]HEXANE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6333428-B1 | TREATMENT OR PREVENTION OF PSYCHIATRIC DISORDERS OR NEUROLOGICAL DISEASES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-1110943-A1 | 6-FLUOROBICYCLO 3. 1.0]HEXANE DERIVATIVES | Taisho Pharmaceutical Co. Ltd. (JP) | 2001-06-27 | — | — | EP | disclosed |