Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 5/20 | 0.43 |
| ▸ | SAT1 | P21673 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80292 | 0.91 | — | — | |
| SCHEMBL28706188 | 0.87 | — | — | |
| SCHEMBL30612397 | 0.87 | CYP2C19 (0.71) | CYP2C19MEN1GLAKMT2ATP53 | |
| SCHEMBL1543426 | 0.87 | CYP2C19 (0.71) | CYP2C19MEN1GLAKMT2ATP53 | |
| Hydrochloric Acid SCHEMBL13859051 | 0.87 | CYP2C19 (0.60) | CYP2C19MEN1GLAKMT2ATP53 | |
| Iodide SCHEMBL7119508 | 0.87 | CYP2C19 (0.60) | CYP2C19MEN1GLAKMT2ATP53 | |
| SCHEMBL11321305 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL2460973 | 0.87 | — | — | |
| SCHEMBL2893263 | 0.87 | CYP2C19 (0.71) | CYP2C19MEN1GLAKMT2ATP53 | |
| Perchlorate SCHEMBL6659115 | 0.82 | CYP2C19 (0.47) | CYP2C19MEN1GLAKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160267-B1 | CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE | JAPAN SCIENCE & TECH CORP (JP) | 2004-08-04 | — | — | EP | disclosed |