Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445668 | 0.90 | PARP1 (0.63) | PARP1PBRM1ALOX15ATMTDP1 | |
| SCHEMBL3177794 | 0.86 | PARP1 (0.59) | PARP1ALOX15ATMTDP1L3MBTL1 | |
| SCHEMBL203108 | 0.86 | PBRM1 (0.67) | PBRM1ATMTDP1L3MBTL1LMNA | |
| SCHEMBL3173817 | 0.86 | PARP1 (0.68) | PARP1ALOX15ATMTDP1L3MBTL1 | |
| SCHEMBL1133114 | 0.84 | ATM (0.71) | PARP1PBRM1ALOX15ATMTDP1 | |
| SCHEMBL31514279 | 0.84 | ATM (0.71) | PARP1PBRM1ALOX15ATMTDP1 | |
| SCHEMBL3444927 | 0.84 | PARP1 (0.65) | PARP1ALOX15ATMTDP1L3MBTL1 | |
| SCHEMBL8437706 | 0.83 | SRD5A2 (0.64) | PARP1ALOX15ATMTDP1L3MBTL1 | |
| SCHEMBL7488057 | 0.83 | MAPK1 (0.64) | PARP1ALOX15ATMTDP1L3MBTL1 | |
| SCHEMBL6651963 | 0.82 | CNR1 (0.53) | PBRM1CA1CA2CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715595-B | Synthesis method of 4-aminobenzophenone compound | 台州学院 | 2025-04-18 | — | — | CN | disclosed |
| CN-116715595-A | Synthesis method of 4-aminobenzophenone compound | 台州学院 | 2023-09-08 | — | — | CN | disclosed |
| EP-0966424-B1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMA AS (DK) | 2004-06-23 | — | — | EP | disclosed |
| US-6313174-B1 | FOR THERAPY AND PROPHYLAXIS OF ASTHMA, ALLERGY, RHEUMATOID ARTHRITIS, SPONDYLOARTHRITIS, GOUT, ATHEROSCLEROSIS, CHRONIC INFLAMMATORY BOWEL DISEASE, PROLIFERATIVE AND INFLAMMATORY SKIN DISORDERS | Leo Pharmaceutical Products Ltd.A/S/ (Løvens kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-11-06 | — | — | US | disclosed |