Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 8/20 | 0.46 |
| ▸ | CDK2 | P24941 | 8/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 8/20 | 0.46 |
| ▸ | IKBKB | O14920 | 9/20 | 0.46 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253419 | 0.91 | CCNA2 (0.46) | CCNA2CDK2CCNA1IKBKBF10 | |
| SCHEMBL5338107 | 0.81 | IKBKB (0.51) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5346277 | 0.81 | IKBKB (0.62) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL14532972 | 0.81 | CCNA2 (0.58) | CCNA2CDK2CCNA1IKBKBAURKA | |
| SCHEMBL6197538 | 0.80 | IKBKB (0.52) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5339480 | 0.80 | CCNA2 (0.63) | CCNA2CDK2CCNA1IKBKBAURKA | |
| SCHEMBL3858859 | 0.80 | CCNA2 (0.43) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL6346387 | 0.79 | CCNA2 (0.50) | CCNA2CDK2CCNA1F10F2 | |
| SCHEMBL5334053 | 0.79 | CCNA2 (0.62) | CCNA2CDK2CCNA1IKBKBAURKA | |
| SCHEMBL5347307 | 0.78 | CCNA2 (0.63) | CCNA2CDK2CCNA1IKBKBF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444207-A2 | SUBSTITUTED PYRAZOLYL-COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003024935-A2 | SUBSTITUTED PYRAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2003-03-27 | — | — | WO | disclosed |