Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658239 | 1.00 | DPP4 (0.49) | DPP4DPP7DPP8DPP9ADRB1 | |
| SCHEMBL6658241 | 1.00 | DPP4 (0.49) | DPP4DPP7DPP8DPP9ADRB1 | |
| SCHEMBL2855150 | 0.82 | DPP4 (0.51) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2855144 | 0.82 | DPP4 (0.51) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2859760 | 0.67 | DPP4 (0.58) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2859755 | 0.67 | DPP4 (0.58) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2859186 | 0.66 | DPP4 (0.51) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2859184 | 0.66 | DPP4 (0.51) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL6678573 | 0.66 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL5375410 | 0.66 | DPP4 (0.54) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426366-A1 | THIAZOLIDINE DERIVATIVE AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2004-06-09 | — | — | EP | disclosed |