Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17755418 | 1.00 | HCAR2 (0.67) | HCAR2ATMMAPTAPPALDH1A1 | |
| SCHEMBL6658420 | 1.00 | HCAR2 (0.67) | HCAR2ATMMAPTAPPALDH1A1 | |
| SCHEMBL1879844 | 0.88 | ATM (0.61) | HCAR2ATMMAPTAPPALDH1A1 | |
| SCHEMBL6661633 | 0.88 | ATM (0.73) | HCAR2ATMMAPTAPPALDH1A1 | |
| SCHEMBL6661635 | 0.88 | ATM (0.73) | HCAR2ATMMAPTAPPALDH1A1 | |
| SCHEMBL1401100 | 0.88 | HCAR2 (0.52) | HCAR2ATMMAPTALDH1A1HPGD | |
| SCHEMBL22588816 | 0.86 | ATM (0.59) | HCAR2ATMMAPTALDH1A1HPGD | |
| SCHEMBL7756691 | 0.86 | HCAR2 (0.55) | HCAR2ATMMAPTAPPALDH1A1 | |
| SCHEMBL28489018 | 0.86 | ATM (0.59) | HCAR2ATMMAPTALDH1A1HPGD | |
| SCHEMBL265418 | 0.84 | MAPT (0.66) | HCAR2ATMMAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123915-B1 | Process for producing alpha, beta-unsaturated carboxylic acid esters and catalyst for use in such process | NIPPON CATALYTIC CHEM IND (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6541656-B2 | Reacting an alpha, beta unsaturated carboxylic acid ester with a heterocyclic oxygen nitrogen, or sulfur compound | NIPPON SHOKUBAI COMPANY, LTD. (JP) | 2003-04-01 | — | — | US | disclosed |
| US-20010034300-A1 | Reacting an alpha, beta unsaturated carboxylic acid ester with a heterocyclic oxygen nitrogen, or sulfur compound | NIPPON SHOKUBAI COMPANY LTD. (JP) | 2001-10-25 | — | — | US | disclosed |
| EP-1123915-A1 | Process for producing alpha, beta-unsaturated carboxylic acid esters and catalyst for use in such process | Nippon Shokubai Co., Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |