Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 6/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658763 | 1.00 | MEN1 (0.32) | MEN1ALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL6664654 | 0.96 | PPARA (0.35) | KDM4ERAB9ARARBPPARATSHR | |
| SCHEMBL6662626 | 0.96 | PPARA (0.35) | KDM4ERAB9ARARBPPARATSHR | |
| SCHEMBL6659237 | 0.94 | KDM4E (0.39) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL6659243 | 0.94 | KDM4E (0.39) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL6658653 | 0.92 | PTPN1 (0.31) | MEN1ALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL6658646 | 0.92 | PTPN1 (0.31) | MEN1ALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL6661259 | 0.91 | PPARA (0.40) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL6661267 | 0.91 | PPARA (0.40) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL6664743 | 0.89 | KDM4E (0.39) | MEN1ALDH1A1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165721-B1 | LIQUID CRYSTALLINE ALKENYL COMPOUNDS INCORPORATING AN HETEROCYCLIC FIVE-MEMBERED RING | QINETIQ LTD (GB) | 2004-08-04 | — | — | EP | disclosed |
| US-6696110-B1 | THERMOGRAPHY | QINETIQ LIMITED (GB) | 2004-02-24 | — | — | US | disclosed |