Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658366 | 1.00 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL6659195 | 1.00 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL6657533 | 1.00 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL6657773 | 1.00 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL6660873 | 1.00 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL6662704 | 1.00 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL6658154 | 1.00 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL6657792 | 1.00 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL29595659 | 0.94 | CYP2D6 (0.47) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL6659708 | 0.92 | SPHK1 (0.50) | SPHK1CYP2D6GMNNLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869185-B9 | Production of optically active sphingoid compound | SUMITOMO CHEMICAL CO (JP) | 2004-08-11 | — | — | EP | claimed |
| EP-0869185-B1 | Production of optically active sphingoid compound | SUMITOMO CHEMICAL CO (JP) | 2003-09-17 | — | — | EP | claimed |
| EP-0869185-B9 | Production of optically active sphingoid compound | SUMITOMO CHEMICAL CO (JP) | 2004-08-11 | — | — | EP | disclosed |
| EP-0869185-B1 | Production of optically active sphingoid compound | SUMITOMO CHEMICAL CO (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6184008-B1 | USING AN ESTERASE TO TO SELECTIVELY HYDROLYZE AN ENANTIOMER OF AN ESTER OF DEFINED STRUCTURE TO PRODUCE THE ALCOHOL; COSMETICS; MEDICINAL TREATMENTS FOR SKIN AND HAIR; CHEMICAL INTERMEDIATES | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0869185-A2 | Production of optically active sphingoid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-07 | — | — | EP | disclosed |