Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.41 |
| ▸ | FAAH | O00519 | 7/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656879 | 0.89 | PTPN11 (0.44) | PTPN11TSHRSMPD1CYP1A2CYP19A1 | |
| SCHEMBL6657967 | 0.89 | PTPN11 (0.44) | PTPN11TSHRSMPD1CYP1A2CYP19A1 | |
| SCHEMBL6661830 | 0.83 | PTPN11 (0.43) | PTPN11TSHRSMPD1CYP1A2CYP19A1 | |
| SCHEMBL6655589 | 0.82 | PTPN11 (0.38) | PTGS2FAAHPTPN11TSHR | |
| SCHEMBL6659101 | 0.79 | PTPN11 (0.39) | FAAHPTPN11TSHR | |
| SCHEMBL6656108 | 0.78 | PTPN11 (0.43) | PTGS2FAAHPTPN11 | |
| SCHEMBL6656977 | 0.78 | PTPN11 (0.41) | FAAHPTPN11TSHR | |
| SCHEMBL6659332 | 0.78 | PTPN11 (0.41) | PTPN11TSHR | |
| SCHEMBL6656143 | 0.77 | POLM (0.41) | PTGS2FAAH | |
| SCHEMBL8208402 | 0.76 | CNR1 (0.43) | PTPN11TSHRSMPD1CYP1A2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160233-B1 | Novel terphenyl compounds | SHARP KK (JP) | 2004-07-21 | — | — | EP | disclosed |
| EP-1160233-A2 | Novel terphenyl compounds | SHARP KABUSHIKI KAISHA (JP) | 2001-12-05 | — | — | EP | disclosed |