⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98184 | 0.72 | — | — | |
| SCHEMBL582903 | 0.72 | — | — | |
| SCHEMBL8763968 | 0.71 | — | — | |
| SCHEMBL644334 | 0.71 | — | — | |
| SCHEMBL19197245 | 0.69 | — | — | |
| SCHEMBL18672372 | 0.69 | — | — | |
| SCHEMBL9544266 | 0.69 | — | — | |
| SCHEMBL6760052 | 0.67 | — | — | |
| SCHEMBL6594058 | 0.67 | — | — | |
| SCHEMBL21539529 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1145716-B1 | Therapeutic agent for the treatment of dermatitis | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2004-08-04 | — | — | EP | disclosed |
| US-6440978-B2 | A THERAPEUTICAL AGENT FOR DERMATITIS COMPRISES 7-AMINO-3-(HALO SUBSTITUTED OR UNSUBSTITUED BENZYL)-1,2,3-TETRAHYDRO-1-PHENYLPYRIDO(2,3-D)PYRIMIDIN-2,4-DIONE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2002-08-27 | — | — | US | disclosed |
| US-20010056097-A1 | Therapeutic agent for dermatitis | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2001-12-27 | — | — | US | disclosed |
| EP-1145716-A2 | Therapeutic agent for the treatment of dermatitis | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2001-10-17 | — | — | EP | disclosed |