Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.53 |
| ▸ | PPARG | P37231 | 15/20 | 0.53 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658219 | 0.92 | PPARA (0.54) | PPARAPPARGKDM4EMEN1KMT2A | |
| SCHEMBL5360256 | 0.91 | PPARA (0.51) | PPARAPPARGPPARDKDM4EMEN1 | |
| SCHEMBL14501884 | 0.91 | PPARA (0.51) | PPARAPPARGPPARDKDM4EMEN1 | |
| SCHEMBL14501935 | 0.91 | PPARA (0.51) | PPARAPPARGPPARDKDM4EMEN1 | |
| SCHEMBL6660840 | 0.88 | PPARA (0.49) | PPARAPPARGPPARDKDM4EMEN1 | |
| SCHEMBL6659254 | 0.85 | PPARA (0.54) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5357732 | 0.84 | PPARA (0.48) | PPARAPPARGPPARDKDM4EMEN1 | |
| SCHEMBL14501941 | 0.83 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL5363024 | 0.83 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL6150741 | 0.83 | PPARA (0.56) | PPARAPPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |