Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 11/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5194392 | 0.89 | ADRB3 (0.64) | ADRB3ADRA1ADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL5194384 | 0.89 | ADRB3 (0.64) | ADRB3ADRA1ADRD2DRD4DRD3 | |
| SCHEMBL5196674 | 0.89 | ADRB3 (0.66) | ADRB3ADRA1ADRD2DRD4DRD3 | |
| SCHEMBL1120904 | 0.88 | ADRB3 (0.63) | ADRB3ADRA1ADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL5193899 | 0.88 | ADRB3 (0.65) | ADRB3ADRA1ADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL5193904 | 0.88 | ADRB3 (0.65) | ADRB3ADRA1ADRD2DRD4DRD3 | |
| SCHEMBL6665771 | 0.88 | ADRB3 (0.66) | ADRB3ADRA1AADRB2ADRB1 | |
| SCHEMBL1120799 | 0.85 | ADRB3 (0.65) | ADRB3ADRA1ADRD2DRD4DRD3 | |
| SCHEMBL1120890 | 0.85 | ADRB3 (0.60) | ADRB3ADRA1ADRD2DRD4DRD3 | |
| SCHEMBL7251755 | 0.85 | ADRB3 (0.66) | ADRB3ADRA1ADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1447400-A1 | BICYCLIC COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2004-08-18 | — | — | EP | disclosed |