Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CDC7 | O00311 | 12/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 12/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23668270 | 0.86 | CDC7 (0.64) | HTTL3MBTL1PKMHPGDMAPK1 | |
| SCHEMBL21639774 | 0.86 | CDC7 (0.63) | HTTL3MBTL1HPGDMAPK1TSHR | |
| SCHEMBL14228864 | 0.86 | CDC7 (0.49) | HTTL3MBTL1HPGDCDC7DBF4 | |
| SCHEMBL21639726 | 0.86 | CDC7 (0.63) | HTTL3MBTL1HPGDCDC7DBF4 | |
| SCHEMBL31186606 | 0.86 | CDC7 (0.63) | HTTL3MBTL1HPGDMAPK1TSHR | |
| SCHEMBL31186608 | 0.86 | CDC7 (0.63) | HTTL3MBTL1HPGDCDC7DBF4 | |
| SCHEMBL2120063 | 0.85 | CDC7 (0.61) | HTTL3MBTL1PKMHPGDCDC7 | |
| SCHEMBL31186612 | 0.85 | CDC7 (0.61) | HTTL3MBTL1PKMHPGDCDC7 | |
| SCHEMBL21639758 | 0.85 | CDC7 (0.65) | HTTL3MBTL1HPGDCDC7DBF4 | |
| SCHEMBL31186604 | 0.85 | CDC7 (0.65) | HTTL3MBTL1HPGDCDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444982-A1 | The use of purine derivatives as selective kinase inhibitors | MERCKLE GMBH (DE) | 2004-08-11 | — | — | EP | disclosed |