SCHEMBL6661360

SCHEMBL6661360

CCN1CCN(CC)CCN(CCN2CCN(CC)CCN(CC)CC2)CC1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.45
CHRNA7 P36544 1/20 0.42
ALOX15 P16050 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
ALDH1A1 P00352 1/20 0.41
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
RAD52 P43351 1/20 0.39
GFER P55789 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
PKM P14618 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL6664467 0.94 KDM1A (0.42) KDM1ACHRNA7ALOX15SIGMAR1ALDH1A1
SCHEMBL10294630 0.91 CYP2D6 (0.46) KDM1ACHRNA7SIGMAR1KMT2A
SCHEMBL22957950 0.91 KDM1A (0.41) KDM1ACHRNA7ALOX15SIGMAR1ALDH1A1
SCHEMBL19020372 0.91 KDM1A (0.41) KDM1ACHRNA7ALOX15SIGMAR1ALDH1A1
SCHEMBL84808 0.89 CHRNA7 (0.48) CHRNA7ALDH1A1KDM4EGAAMAPT
SCHEMBL6657817 0.89 CHRNA7 (0.48) CHRNA7ALDH1A1KDM4EGAAMAPT
SCHEMBL262312 0.89
SCHEMBL577052 0.89 CHRNA7 (0.48) CHRNA7ALDH1A1KDM4EGAAMAPT
SCHEMBL577415 0.89 CHRNA7 (0.48) CHRNA7ALDH1A1KDM4EGAAMAPT
SCHEMBL13061597 0.88 HRH3 (0.50) KDM1AALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1160267-B1 CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE JAPAN SCIENCE & TECH CORP (JP) 2004-08-04 EP disclosed
US-6689919-B1 SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-02-10 US disclosed