Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CTSK | P43235 | 9/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29681372 | 1.00 | CA1 (0.56) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL2519000 | 1.00 | CA1 (0.56) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL24554689 | 1.00 | CA1 (0.56) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL12378785 | 0.86 | CA1 (0.56) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL12378790 | 0.86 | CA1 (0.56) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL4549626 | 0.85 | CA1 (0.54) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL24136470 | 0.85 | CA1 (0.58) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL1809665 | 0.84 | CA1 (0.71) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL1414602 | 0.84 | CA1 (0.71) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL1134642 | 0.84 | CA1 (0.71) | CA1CA2CA7CTSKCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448529-A1 | SULFONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE DISEASES AND ALLERGIES | SMITHKLINE BEECHAM PLC (GB) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045922-A1 | SULFONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE DISEASES AND ALLERGIES | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-06-05 | — | — | WO | disclosed |