Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL29042454 | 0.96 | — | — | |
| Sulfuric Acid SCHEMBL1889472 | 0.85 | BLM (0.53) | TSHRTDP1BLMLMNASLC6A6 | |
| Sulfuric Acid SCHEMBL11192447 | 0.85 | BLM (0.53) | TSHRTDP1BLMLMNASLC6A6 | |
| Sulfuric Acid SCHEMBL5542358 | 0.81 | BLM (0.56) | TSHRTDP1BLMLMNASLC6A6 | |
| Sulfuric Acid SCHEMBL28561656 | 0.81 | BLM (0.56) | TSHRTDP1BLMLMNASLC6A6 | |
| Sulfuric Acid SCHEMBL728848 | 0.81 | — | — | |
| Sulfuric Acid SCHEMBL8042286 | 0.81 | BLM (0.56) | TSHRTDP1BLMLMNASLC6A6 | |
| SCHEMBL28677037 | 0.80 | — | — | |
| SCHEMBL3941836 | 0.80 | TSHR (0.89) | TSHRTDP1BLMCA2CA5A | |
| Thiosulfuric Acid SCHEMBL28980179 | 0.79 | BLM (0.47) | TSHRBLMLMNASLC6A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160267-B1 | CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE | JAPAN SCIENCE & TECH CORP (JP) | 2004-08-04 | — | — | EP | disclosed |