Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661748 | 1.00 | CA12 (0.54) | CA12CA1CA2TYRCA7 | |
| SCHEMBL2131663 | 0.87 | CA12 (0.70) | CA12CA1CA2TYRCA7 | |
| SCHEMBL2131661 | 0.87 | CA12 (0.70) | CA12CA1CA2TYRCA7 | |
| SCHEMBL2651781 | 0.84 | CA12 (0.56) | CA12CA1CA2TYRCA7 | |
| SCHEMBL14878501 | 0.84 | CA12 (0.77) | CA12CA1CA2TYRCA7 | |
| SCHEMBL30157231 | 0.84 | CA12 (0.77) | CA12CA1CA2TYRCA7 | |
| SCHEMBL23823901 | 0.83 | CA12 (0.54) | CA12CA1CA2TYRCA7 | |
| SCHEMBL21428246 | 0.83 | HDAC8 (0.68) | CA12CA1CA2TYRCA7 | |
| SCHEMBL29980425 | 0.83 | CA12 (0.54) | CA12CA1CA2TYRCA7 | |
| SCHEMBL29980103 | 0.83 | HDAC8 (0.68) | CA12CA1CA2TYRCA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004007445-A2 | PROTEIN KINASE C MODULATORS, AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2004-01-22 | — | — | WO | disclosed |