Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662000 | 0.92 | PDE2A (0.35) | PDE2ACACNA1HCASRPDE4A | |
| SCHEMBL6660713 | 0.88 | PDE2A (0.41) | PDE2ATRPV1HTR2AFAAHCACNA1H | |
| SCHEMBL6661305 | 0.88 | PDE4A (0.38) | PDE2ACACNA1HCASRPDE4A | |
| SCHEMBL6662209 | 0.87 | HTR2A (0.34) | TRPV1HTR2AFAAHRARBRARA | |
| SCHEMBL6663948 | 0.87 | HTR2A (0.37) | TRPV1HTR2AFAAHRARBRARA | |
| SCHEMBL6662865 | 0.84 | HTR2A (0.39) | TRPV1HTR2AFAAHRARBRARA | |
| SCHEMBL6666303 | 0.84 | TRPV1 (0.36) | TRPV1HTR2AFAAHRARBRARA | |
| SCHEMBL6660727 | 0.83 | PPARA (0.39) | HTR2AFAAH | |
| SCHEMBL6662955 | 0.83 | HTR2A (0.42) | TRPV1HTR2AFAAH | |
| SCHEMBL7730786 | 0.82 | HTR2A (0.35) | HTR2AFAAHCACNA1HRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |