Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 0.64 |
| ▸ | FNTB | P49356 | 20/20 | 0.64 |
| ▸ | HRAS | P01112 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 1/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6618150 | 1.00 | FNTA (0.64) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3498521 | 0.87 | FNTA (0.65) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL7689881 | 0.84 | FNTA (0.59) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL6616926 | 0.84 | FNTA (0.59) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3499345 | 0.83 | FNTA (0.72) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3499338 | 0.83 | FNTA (0.72) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3501350 | 0.79 | FNTA (0.77) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3501345 | 0.79 | FNTA (0.77) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL3687679 | 0.79 | FNTA (0.76) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL6633522 | 0.78 | FNTA (0.46) | FNTAFNTBHRASKRASPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481975-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |