Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16074762 | 0.91 | TRPV1 (0.50) | TRPV1TRPA1SPHK1PTPN1CYP2D6 | |
| SCHEMBL11410290 | 0.91 | TRPV1 (0.50) | TRPV1TRPA1SPHK1PTPN1CYP2D6 | |
| SCHEMBL16074675 | 0.91 | TRPV1 (0.50) | TRPV1TRPA1SPHK1PTPN1CYP2D6 | |
| SCHEMBL16074863 | 0.91 | TRPV1 (0.50) | TRPV1TRPA1SPHK1PTPN1CYP2D6 | |
| SCHEMBL16074889 | 0.91 | TRPV1 (0.50) | TRPV1TRPA1SPHK1PTPN1CYP2D6 | |
| SCHEMBL16074937 | 0.91 | TRPV1 (0.50) | TRPV1TRPA1SPHK1PTPN1CYP2D6 | |
| SCHEMBL16074741 | 0.91 | TRPV1 (0.50) | TRPV1TRPA1SPHK1PTPN1CYP2D6 | |
| SCHEMBL16074945 | 0.91 | TRPV1 (0.50) | TRPV1TRPA1SPHK1PTPN1CYP2D6 | |
| SCHEMBL16074914 | 0.91 | TRPV1 (0.50) | TRPV1TRPA1SPHK1PTPN1CYP2D6 | |
| SCHEMBL16074850 | 0.91 | TRPV1 (0.50) | TRPV1TRPA1SPHK1PTPN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482997-A1 | AnB BLOCK COPOLYMERS CONTAINING POLY(VINYL PYRROLIDONE) UNITS, MEDICAL DEVICES, AND METHODS | Medtronic, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| EP-1446437-A1 | COMPOUNDS CONTAINING QUATERNARY CARBONS, MEDICAL DEVICES, AND METHODS | Medtronic, Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003072158-A1 | AnB BLOCK COPOLYMERS CONTAINING POLY(VINYL PYRROLIDONE) UNITS, MEDICAL DEVICES, AND METHODS | MEDTRONIC,INC. (US) | 2003-09-04 | — | — | WO | disclosed |
| WO-2003042273-A1 | COMPOUNDS CONTAINING QUATERNARY CARBONS, MEDICAL DEVICES, AND METHODS | MEDTRONIC, INC. (US) | 2003-05-22 | — | — | WO | disclosed |