Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | CRHBP | P24387 | 1/20 | 0.70 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.55 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662764 | 1.00 | MEN1 (0.70) | MEN1KMT2AKDM4EALDH1A1USP2 | |
| SCHEMBL6598777 | 0.83 | MEN1 (1.00) | MEN1KMT2AKDM4EALDH1A1USP2 | |
| SCHEMBL6598781 | 0.83 | MEN1 (1.00) | MEN1KMT2AKDM4EALDH1A1USP2 | |
| SCHEMBL16211019 | 0.80 | PSD (0.55) | MEN1KMT2AKDM4EALDH1A1USP2 | |
| SCHEMBL16211020 | 0.80 | PSD (0.55) | MEN1KMT2AKDM4EALDH1A1USP2 | |
| SCHEMBL6684366 | 0.79 | KMT2A (0.46) | MEN1KMT2AKDM4EALDH1A1USP2 | |
| SCHEMBL6664657 | 0.78 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1USP2 | |
| SCHEMBL6664624 | 0.77 | PSD (0.52) | MEN1KMT2AKDM4EALDH1A1USP2 | |
| SCHEMBL6594511 | 0.76 | MEN1 (0.88) | MEN1KMT2AKDM4EALDH1A1USP2 | |
| SCHEMBL6594515 | 0.76 | MEN1 (0.88) | MEN1KMT2AKDM4EALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |