Bromide

Bromide

SCHEMBL6662769

CN1CCN(C)CCN(CCCN2CCN(C)CCN(C)CC2)CC1.[Br-].[Br-].[Br-].[Br-].[Cu+2].[Cu+2]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.40
CHRM4 known ✓ P08173 1/20 0.40
CHRM5 known ✓ P08912 1/20 0.40
CHRM1 known ✓ P11229 1/20 0.40
CHRM3 known ✓ P20309 1/20 0.40
PAOX Q6QHF9 1/20 0.50
CSNK2A2 P19784 2/20 0.48
CSNK2B P67870 2/20 0.48
CSNK2A1 P68400 2/20 0.48
CSNK2A3 Q8NEV1 2/20 0.48
SIGMAR1 Q99720 1/20 0.47
KDM1A O60341 1/20 0.44
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
MAPT P10636 1/20 0.40
HTR1A P08908 1/20 0.40
DRD2 P14416 1/20 0.40
HTR2A P28223 1/20 0.40
HTR6 P50406 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14500306 0.94 PAOX (0.54) PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL6657767 0.94 PAOX (0.54) PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL20234244 0.88 PAOX (0.60) PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL6663287 0.88 PAOX (0.60) PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL12578821 0.86 HRH3 (0.57) PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL31632718 0.85 PAOX (0.64) PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL6659222 0.85 PAOX (0.64) PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL15340848 0.85 PAOX (0.64) PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL31632710 0.85 PAOX (0.64) PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL3437038 0.83 HRH3 (0.62) PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1160267-B1 CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE JAPAN SCIENCE & TECH CORP (JP) 2004-08-04 EP disclosed