Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845357 | 0.70 | HTR1B (0.47) | HPGDKDM4EKMT2A | |
| SCHEMBL6662842 | 0.70 | SMN1; SMN2 (0.45) | HPGDALDH1A1GAAADORA2BADORA3 | |
| SCHEMBL31078875 | 0.68 | NR2E1 (0.60) | HPGDALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL12660565 | 0.68 | NR2E1 (0.60) | HPGDALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL2309545 | 0.68 | NR2E1 (0.60) | HPGDALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL2313731 | 0.65 | TAAR1 (0.50) | KDM4EHSD17B10MAPK1 | |
| SCHEMBL11837496 | 0.65 | PARP14 (0.42) | HSD17B10MAPK1 | |
| SCHEMBL7666158 | 0.65 | MAPKAPK2 (0.59) | — | |
| SCHEMBL28562224 | 0.64 | KMT2A (0.60) | ALDH1A1KDM4EGAAHSD17B10ADORA2B | |
| SCHEMBL1519356 | 0.64 | HTR2A (0.75) | L3MBTL1POLBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014921-A1 | 5,6-FUSED URACIL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |