Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31622785 | 1.00 | TSHR (0.67) | TSHRRAD52NPSR1NAAAHCAR2 | |
| SCHEMBL6663986 | 1.00 | TSHR (0.67) | TSHRRAD52NPSR1NAAAHCAR2 | |
| SCHEMBL5050880 | 1.00 | TSHR (0.67) | TSHRRAD52NPSR1NAAAHCAR2 | |
| SCHEMBL6656362 | 1.00 | TSHR (0.67) | TSHRRAD52NPSR1NAAAHCAR2 | |
| SCHEMBL2522294 | 0.98 | TSHR (0.63) | TSHRRAD52NPSR1NAAAHCAR2 | |
| SCHEMBL6655862 | 0.92 | TSHR (0.55) | TSHRRAD52NPSR1NAAAHCAR2 | |
| SCHEMBL28193251 | 0.92 | TSHR (0.57) | TSHRRAD52NPSR1NAAAHCAR2 | |
| SCHEMBL6658710 | 0.90 | TSHR (0.74) | TSHRRAD52NPSR1NAAAHCAR2 | |
| SCHEMBL5871868 | 0.90 | TSHR (0.74) | TSHRRAD52NPSR1NAAAHCAR2 | |
| SCHEMBL6656457 | 0.90 | TSHR (0.74) | TSHRRAD52NPSR1NAAAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123915-B1 | Process for producing alpha, beta-unsaturated carboxylic acid esters and catalyst for use in such process | NIPPON CATALYTIC CHEM IND (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6541656-B2 | Reacting an alpha, beta unsaturated carboxylic acid ester with a heterocyclic oxygen nitrogen, or sulfur compound | NIPPON SHOKUBAI COMPANY, LTD. (JP) | 2003-04-01 | — | — | US | disclosed |
| US-20010034300-A1 | Reacting an alpha, beta unsaturated carboxylic acid ester with a heterocyclic oxygen nitrogen, or sulfur compound | NIPPON SHOKUBAI COMPANY LTD. (JP) | 2001-10-25 | — | — | US | disclosed |
| EP-1123915-A1 | Process for producing alpha, beta-unsaturated carboxylic acid esters and catalyst for use in such process | Nippon Shokubai Co., Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |