SCHEMBL6663532

SCHEMBL6663532

C=CC(=O)O[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.38
HPGD P15428 1/20 0.38
ALDH1A1 P00352 4/20 0.37
TP53 P04637 2/20 0.37
HIF1A Q16665 2/20 0.37
CYP3A4 P08684 1/20 0.37
HSD17B10 Q99714 1/20 0.37
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28646721 0.96 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL26827372 0.91 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL15746185 0.88 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL14272586 0.84 TSHR (0.33) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2744364 0.82 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28403841 0.82 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL138778 0.80
SCHEMBL2403494 0.80 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28320704 0.79 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2743969 0.79 TSHR (0.35) TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218228-A1 LOW MELT POINT METAL BASED THERMAL INTERFACE MATERIAL SOLSTICE ADVANCED MATERIALS US, INC. 2024-07-04 US disclosed
WO-2021043051-A1 HIGH-PERFORMANCE HEAT CONDUCTING INTERFACE MATERIAL AND APPLICATION THEREOF 上海阿莱德实业股份有限公司 2021-03-11 WO disclosed
WO-2021043052-A1 METHOD FOR PREPARING THERMALLY CONDUCTIVE INTERFACE MATERIAL 上海阿莱德实业股份有限公司 2021-03-11 WO disclosed
US-9617361-B2 Conductive member for electrophotographic image forming apparatus SUMITOMO RIKO COMPANY LIMITED (JP) 2017-04-11 US disclosed
US-9095870-B2 Conductive roll SUMITOMO RIKO COMPANY LIMITED (JP) 2015-08-04 US disclosed
US-20140248067-A1 MODIFIED POLYMER BODY TOKAI RUBBER INDUSTRIES, LTD. (JP) 2014-09-04 US disclosed
US-20130084428-A1 MODIFIED POLYMER SUBSTRATE AND METHOD FOR PRODUCING THE SAME, AND SURFACE TREATMENT AGENT TOKAI RUBBER INDUSTRIES, LTD. (JP) 2013-04-04 US disclosed
US-20130053229-A1 CONDUCTIVE ROLL TOKAI RUBBER INDUSTRIES, LTD. (JP) 2013-02-28 US disclosed
CN-1537249-A Oxygen Permeable Hard Contact Lenses 可乐丽股份有限公司 2004-10-13 CN disclosed
EP-1154287-B1 Oxygen permeable contact lens having a hydrophilic surface and method for producing the same MENICON CO LTD (JP) 2004-09-01 EP disclosed
EP-0713106-B1 Oxygen permeable contact lens having a hydrophilic surface and method for producing the same MENICON CO LTD (JP) 2002-08-14 EP disclosed
EP-1154287-A2 Oxygen permeable contact lens having a hydrophilic surface and method for producing the same Menicon Co., Ltd. (JP) 2001-11-14 EP disclosed
US-5910518-A PROTECTIVE COATINGS COMPRISING HYDROPHILICITY RENDERING MATERIAL AND SURFACTANT; GOOD APPEARNCE, WETTABILITY AND DURABILITY MENICON CO., LTD. (JP) 1999-06-08 US disclosed
US-5708050-A POLYETHERSILOXANES FOR HYDROPHILIC LENSES MENICON CO., LTD. (JP) 1998-01-13 US disclosed
EP-0713106-A1 Oxygen permeable contact lens having a hydrophilic surface and method for producing the same Menicon Co., Ltd. (JP) 1996-05-22 EP disclosed