Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067935 | 0.79 | CA1 (0.54) | CA12CA1CA2CA9 | |
| SCHEMBL5230987 | 0.79 | CCNA2 (0.42) | — | |
| SCHEMBL12886452 | 0.69 | CCNA2 (0.37) | — | |
| SCHEMBL5231014 | 0.64 | CCNA2 (0.62) | — | |
| SCHEMBL5232593 | 0.63 | CCNA2 (0.74) | — | |
| SCHEMBL10653112 | 0.62 | TLR9 (0.39) | — | |
| SCHEMBL1082207 | 0.61 | GLA (0.69) | CA12CA9 | |
| SCHEMBL5225835 | 0.60 | CCNA2 (0.57) | — | |
| SCHEMBL5228506 | 0.59 | CCNA2 (0.46) | — | |
| SCHEMBL13913086 | 0.59 | CA1 (0.47) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478357-A2 | TRICYCLIC PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2004-11-24 | — | — | EP | claimed |
| WO-2003070236-A2 | TRICYCLIC PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA S.P.A. (IT) | 2003-08-28 | — | — | WO | claimed |