⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4973748 | 1.00 | CRBN (0.47) | — | |
| Diketopiperazine SCHEMBL27918928 | 1.00 | CRBN (0.47) | — | |
| SCHEMBL31296913 | 1.00 | CRBN (0.47) | — | |
| Diketopiperazine SCHEMBL28146006 | 0.96 | — | — | |
| Diketopiperazine SCHEMBL27582980 | 0.96 | — | — | |
| Diketopiperazine SCHEMBL28179063 | 0.96 | — | — | |
| Diketopiperazine SCHEMBL9015000 | 0.96 | CRBN (0.44) | — | |
| Diketopiperazine SCHEMBL4370691 | 0.92 | CRBN (0.41) | — | |
| SCHEMBL775329 | 0.91 | — | — | |
| Diketopiperazine SCHEMBL28303441 | 0.89 | CRBN (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3681 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600990-B2 | MRNA induced expression of bone morphogenic protein and receptor and methods related thereto | MULLIN PATENTS, LLC | 2026-04-14 | — | — | US | claimed |
| CN-120192525-A | Preparation method of bio-based semi-crystalline semi-aromatic furan polyamide | 江苏泰阿生物技术有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-115448950-B | Preparation method of L-glufosinate-ammonium intermediate | 中国药科大学 | 2025-05-16 | — | — | CN | claimed |
| WO-2025081013-A1 | JUNCTION OPENER PROTEIN AND NANOPARTICLE COMPOSITIONS AND USES THEREOF | HDT BIO CORP. (US) | 2025-04-17 | — | — | WO | claimed |
| WO-2025080945-A1 | LIPID NANOPARTICLES | CodeBridgeBio Inc. (US) | 2025-04-17 | — | — | WO | claimed |
| WO-2025020846-A1 | 2,5-DIKETOPIPERAZINE COMPOUNDS AND USE THEREOF | 青岛海合生物科技有限公司 | 2025-01-30 | — | — | WO | claimed |
| CN-119371407-A | 2, 5-Diketopiperazine compound with anti-tumor effect and application thereof in preparing medicament for treating and/or preventing neutropenia | 青岛海合生物科技有限公司 | 2025-01-28 | — | — | CN | claimed |
| US-20250000959-A1 | NUCLEIC ACID MOLECULES, FUSION PROTEINS, AND MRNA VACCINES WITH ENHANCED ANTIGEN PRESENTATION BY RECRUITING LIGANDS | WESTGENE BIOPHARMA CO LTD (CN) | 2025-01-02 | — | — | US | claimed |
| CN-116375654-B | Method for preparing 2, 5-diketopiperazine from diglycolamine | 湖北三峡实验室 | 2024-12-31 | — | — | CN | claimed |
| CN-119215016-A | Targeting drug-carrying system capable of penetrating blood brain barrier and preparation method and application thereof | 上海市第六人民医院 | 2024-12-31 | — | — | CN | claimed |
| US-4694081-A | FUNGICIDES | MONSANTO COMPANY (US) | 1987-09-15 | — | — | US | claimed |
| EP-0102694-B1 | METHOD FOR PREPARATION OF N-PHOSPHONOMETHYLGLYCINE | STAUFFER CHEMICAL COMPANY (US) | 1987-09-09 | — | — | EP | claimed |
| EP-0216745-A1 | Process for the preparation of N-substituted aminomethylphosphonic acids | Monsanto Company (US) | 1987-04-01 | — | — | EP | claimed |
| EP-0216746-A2 | Process to prepare 2,5-diketopiperazines | Monsanto Company (US) | 1987-04-01 | — | — | EP | claimed |
| EP-0102694-A1 | Method for preparation of N-phosphonomethylglycine | STAUFFER CHEMICAL COMPANY (US) | 1984-03-14 | — | — | EP | claimed |
| EP-0027189-B1 | 2.5-DIKETOPIPERAZINE-DERIVATIVE, PROCESS FOR ITS PREPARATION AND ITS USE | BAYER AG (DE) | 1984-02-22 | — | — | EP | claimed |
| US-4400330-A | Method for preparation of N-phosphonomethylglycine | STAUFFER CHEMICAL COMPANY (US) | 1983-08-23 | — | — | US | claimed |
| US-4111826-A | ACTIVATOR, STABILIZER, NONIONIC SURFACTANT | LEVER BROTHERS COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| US-4072712-A | FROM ISOCYANATES, CATALYSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-02-07 | — | — | US | claimed |
| US-3979320-A | Liquid crystal composition | HODOGAYA CHEMICAL CO., LTD. (JA) | 1976-09-07 | — | — | US | claimed |