SCHEMBL6663883

SCHEMBL6663883

CCCCCc1ccc(CCOC(F)(F)c2ccc([C@H]3CC[C@H](CCC)CC3)c(F)c2F)cc1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 15/20 0.36
HRH3 Q9Y5N1 2/20 0.34
SPHK2 Q9NRA0 7/20 0.33
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6665213 0.96 SPHK1 (0.36) SPHK1HRH3SPHK2FAAH
SCHEMBL6662147 0.93 OPRL1 (0.32) HRH3
SCHEMBL6665024 0.92 SPHK1 (0.38) SPHK1HRH3SPHK2
SCHEMBL6660732 0.92 SPHK1 (0.38) SPHK1HRH3SPHK2
SCHEMBL6660750 0.92 HRH3 (0.32) SPHK1HRH3
SCHEMBL6665200 0.91 CYP2C9 (0.39) SPHK1HRH3SPHK2
SCHEMBL6667396 0.90 SPHK1 (0.40) SPHK1HRH3SPHK2
SCHEMBL6665094 0.90 S1PR1 (0.35) SPHK1
SCHEMBL6665075 0.90 S1PR1 (0.34)
SCHEMBL6666669 0.88 CYP2C9 (0.37) SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed