SCHEMBL6663918

SCHEMBL6663918

C=CCCc1ccc(CCOC(F)(F)c2ccc([C@H]3CC[C@H](C=C)CC3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.31
SPHK1 Q9NYA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6666723 0.95 HTR2C (0.34) HTR2CSPHK1
SCHEMBL6662950 0.92 ESR2 (0.32)
SCHEMBL6664061 0.92 ESR2 (0.32)
SCHEMBL6667749 0.92 HTR2C (0.40) HTR2CSPHK1
SCHEMBL6665718 0.90 SPHK1 (0.30) SPHK1
SCHEMBL6665964 0.90 SPHK1 (0.30) SPHK1
SCHEMBL6661099 0.89 ESR2 (0.35) HTR2CSPHK1
SCHEMBL6664155 0.89 ESR2 (0.33) HTR2C
SCHEMBL6663932 0.87 SPHK1 (0.31) SPHK1
SCHEMBL6664872 0.87 GRM2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed