Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663203 | 0.93 | CYP2C9 (0.34) | JAK2JAK1TYK2JAK3MAPT | |
| SCHEMBL6665636 | 0.91 | MEN1 (0.32) | — | |
| SCHEMBL6663478 | 0.89 | PDE2A (0.37) | — | |
| SCHEMBL6663818 | 0.89 | CYP11B1 (0.31) | — | |
| SCHEMBL6666314 | 0.88 | JAK2 (0.32) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL6665832 | 0.88 | MAPT (0.34) | JAK2JAK1TYK2JAK3GAA | |
| SCHEMBL6664208 | 0.87 | PDE2A (0.33) | — | |
| SCHEMBL6666642 | 0.86 | GRM2 (0.31) | — | |
| SCHEMBL6661630 | 0.86 | — | — | |
| SCHEMBL6663967 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |