Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 16/20 | 0.80 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.58 |
| ▸ | FPR3 | P25089 | 1/20 | 0.51 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6077066 | 0.94 | CCR1 (0.77) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL4589294 | 0.92 | CCR1 (0.77) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL4589298 | 0.92 | CCR1 (0.77) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL4589300 | 0.92 | CCR1 (0.77) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL4587967 | 0.90 | CCR1 (0.74) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL5060159 | 0.90 | CCR1 (0.74) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL4587970 | 0.90 | CCR1 (0.74) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL4587972 | 0.90 | CCR1 (0.74) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL5060162 | 0.90 | CCR1 (0.74) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL5060156 | 0.90 | CCR1 (0.74) | CCR1PTGDR2FPR3GPR65GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438298-A1 | PIPERAZINE DERIVATIVES WITH CCR1 RECEPTOR ANTAGONIST ACTIVITY | Pfizer Products Inc. (US) | 2004-07-21 | — | — | EP | claimed |
| WO-2003035627-A1 | PIPERAZINE DERIVATIVES WITH CCR1 RECEPTOR ANTAGONIST ACTIVITY | PFIZER PRODUCTS INC. (US) | 2003-05-01 | — | — | WO | claimed |
| EP-1438298-A1 | PIPERAZINE DERIVATIVES WITH CCR1 RECEPTOR ANTAGONIST ACTIVITY | Pfizer Products Inc. (US) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003035627-A1 | PIPERAZINE DERIVATIVES WITH CCR1 RECEPTOR ANTAGONIST ACTIVITY | PFIZER PRODUCTS INC. (US) | 2003-05-01 | — | — | WO | disclosed |