SCHEMBL666417

SCHEMBL666417

FC(F)(F)C1(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C2(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C21F

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10409113 0.84 MEN1 (0.40) MEN1KMT2ATDP1
SCHEMBL3160608 0.80 MEN1 (0.42) MEN1KMT2ATDP1
SCHEMBL1280066 0.79 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL297814 0.79 MEN1 (0.33) MEN1KMT2ATDP1
Perfluorocyclobutane SCHEMBL10391737 0.79 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL555524 0.79 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL149623 0.79 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL6885374 0.79 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL3151340 0.79 MEN1 (0.47) MEN1KMT2ATDP1
SCHEMBL3150843 0.78 MEN1 (0.40) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240408173-A1 SILK FIBROIN-CONTAINING COMPOSITION AND METHODS OF USE THEREOF GEORGETOWN UNIVERSITY 2024-12-12 US claimed
US-20210121525-A1 SILK FIBROIN-CONTAINING COMPOSITION AND METHODS OF USE THEREOF GEORGETOWN UNIVERSITY 2021-04-29 US claimed
WO-2019079661-A1 SILK FIBROIN-CONTAINING COMPOSITION AND METHODS OF USE THEREOF GEORGETOWN UNIVERSITY (US) 2019-04-25 WO claimed
EP-1214586-B1 IMPLANTABLE GLUCOSE SENSOR OXYGEN BIOTHERAPEUTICS INC (US) 2010-03-24 EP claimed
US-6815186-B2 COMPRISES GLUCOSE OXIDASE EMULSION WITH PERFLUOROCARBON WHICH IS USED WITH MINIATURE POLAROGRAPHIC DEVICE; GELS IMPLANTED BIOSYSTEMS, INC. 2004-11-09 US claimed
JP-3498144-B2 2004-02-16 JP claimed
US-6458376-B1 Nonaqueous fluorinated drug delivery suspensions ALLERGAN, INC. 2002-10-01 US claimed
WO-2001020019-A9 IMPLANTABLE GLUCOSE SENSOR IMPLANTED BIOSYSTEMS INC (US) 2002-08-29 WO claimed
EP-0758886-B1 USE OF PERFLUOROCARBONS FOR ASSISTING NORMAL BREATHING IN MAMMALS HAVING LUNG DISORDERS SYNTHETIC BLOOD INTERNATIONAL (US) 2002-07-24 EP claimed
EP-1214586-A2 IMPLANTABLE GLUCOSE SENSOR Implanted Biosystems, Inc. (US) 2002-06-19 EP claimed
EP-0089232-B1 PERFLUOROCARBON LIQUIDS USEFUL IN EYE TREATMENT AND DIAGNOSTIC PROCEDURES CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1986-07-02 EP claimed
US-4586511-A Methods and compositions for detecting and imaging a gas in an animal by nuclear magnetic resonance CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1986-05-06 US claimed
US-4490351-A REPLACEMENT FOR VITREOUS AND AQUEOUS; TRANSPARENTIZES LENS AND CORNEA; SURGERY; MEDICAL DIAGNOSIS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1984-12-25 US claimed
EP-0112658-A2 Extraocular device for treating the eye CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1984-07-04 EP claimed
US-4452818-A Extraocular method of treating the eye with liquid perfluorocarbons HAIDT STERLING J (US) 1984-06-05 US claimed
US-4443480-A PERFLUOROCYCLOCARBON, AMINE OXIDE CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1984-04-17 US claimed
EP-0091820-A1 Artificial blood and other gas transport agents CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1983-10-19 EP claimed
EP-0033402-B1 PERFUSATE FOR PRESERVING ORGAN TO BE TRANSPLANTED AND PRESERVING METHOD The Green Cross Corporation (JP) 1983-09-07 EP claimed
EP-0033402-A1 Perfusate for preserving organ to be transplanted and preserving method The Green Cross Corporation (JP) 1981-08-12 EP claimed
US-4186253-A RINGER'S SOLUTION WITH INCREASED POTASSIUM ION, ALBUMIN, PERFLUOROCARBON COMPOUND, EMULSIFIER THE GREEN CROSS CORPORATION (JP) 1980-01-29 US claimed