SCHEMBL6665283

SCHEMBL6665283

CC=C[C@H]1CC[C@H](CC(F)(F)OCc2ccc([C@H]3CC[C@H](C=CC)CC3)cc2)CC1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 8/20 0.34
ESR1 P03372 6/20 0.33
CYP2C9 P11712 3/20 0.33
CYP3A4 P08684 2/20 0.33
HDAC2 Q92769 1/20 0.32
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6665279 1.00 ESR2 (0.34) ESR2ESR1CYP2C9CYP3A4HDAC2
SCHEMBL6665272 1.00 ESR2 (0.34) ESR2ESR1CYP2C9CYP3A4HDAC2
SCHEMBL6663187 0.95 ESR2 (0.32) ESR2ESR1CYP2C9CYP3A4HDAC2
SCHEMBL6663190 0.95 ESR2 (0.32) ESR2ESR1CYP2C9CYP3A4HDAC2
SCHEMBL6667112 0.95 ESR2 (0.37) ESR2ESR1CYP2C9CYP3A4HDAC2
SCHEMBL6667108 0.95 ESR2 (0.37) ESR2ESR1CYP2C9CYP3A4HDAC2
SCHEMBL6667110 0.95 ESR2 (0.37) ESR2ESR1CYP2C9CYP3A4HDAC2
SCHEMBL6663182 0.95 ESR2 (0.32) ESR2ESR1CYP2C9CYP3A4HDAC2
SCHEMBL6664001 0.94 ESR2 (0.31) ESR2
SCHEMBL6666457 0.94 CYP2C9 (0.39) ESR2CYP2C9HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed