SCHEMBL6665484

SCHEMBL6665484

CC(CNCCC(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.57
HRH1 P35367 3/20 0.57
KCNH2 Q12809 4/20 0.56
OPRM1 P35372 3/20 0.56
CYP3A4 P08684 2/20 0.56
HTR1A P08908 2/20 0.56
ADORA3 P0DMS8 2/20 0.56
SLC6A2 P23975 2/20 0.56
SLC6A4 P31645 2/20 0.56
ADRA1A P35348 2/20 0.56
DRD3 P35462 2/20 0.56
SLC6A3 Q01959 2/20 0.56
CHRM2 P08172 1/20 0.56
ADRA2A P08913 1/20 0.56
CHRM1 P11229 1/20 0.56
SMPD1 P17405 1/20 0.56
DRD1 P21728 1/20 0.56
TBXA2R P21731 1/20 0.56
CASR P41180 1/20 0.56
HTR2B P41595 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3643077 0.86 HTR2A (0.59) HTR2AHRH1KCNH2OPRM1CYP3A4
SCHEMBL11046082 0.83 TAAR1 (0.68) TAAR1AOC3MEN1KMT2A
SCHEMBL20689708 0.82 GRIN1 (0.66) TAAR1AOC3MEN1KMT2AALDH1A1
SCHEMBL20689710 0.82 GRIN1 (0.66) TAAR1AOC3MEN1KMT2AALDH1A1
SCHEMBL20689725 0.82 GRIN1 (0.66) TAAR1AOC3MEN1KMT2AALDH1A1
SCHEMBL23081526 0.82 TAAR1 (0.57) TAAR1AOC3MEN1KMT2AALDH1A1
SCHEMBL13911257 0.82 TAAR1 (0.57) TAAR1AOC3MEN1KMT2AALDH1A1
SCHEMBL17308024 0.82 TAAR1 (0.61) KCNH2OPRM1HTR1AADORA3SLC6A2
SCHEMBL11796932 0.81 KCNH2 (0.76) HTR2AHRH1KCNH2OPRM1CYP3A4
SCHEMBL14065005 0.81 TAAR1 (0.50) HTR2AHRH1KCNH2OPRM1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0105872-B1 NOVEL COSMETIC COMPOSITIONS CONTAINING PRENYLAMINE AND A PROCESS FOR THEIR PREPARATION CAOLA KOZMETIKAI ES HAZTARTÄSVEGYIPARI VALLALAT (HU) 1988-03-30 EP claimed
WO-2004010790-A1 SWEET PRODUCTS WITH FLAVIN CONTENT AND METHODS OF PRODUCING THEREOF HORVATH ISTVAN (HU) 2004-02-05 WO disclosed
EP-0105872-B1 NOVEL COSMETIC COMPOSITIONS CONTAINING PRENYLAMINE AND A PROCESS FOR THEIR PREPARATION CAOLA KOZMETIKAI ES HAZTARTÄSVEGYIPARI VALLALAT (HU) 1988-03-30 EP disclosed
US-4259257-A ANTI-ANGINOSE ACTIVITY EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1981-03-31 US disclosed
US-4191777-A Maleic acid halfamides having blood pressure raising activity DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-03-04 US disclosed