SCHEMBL6665503

SCHEMBL6665503

BrCCC1CCOO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2683423 0.86
SCHEMBL4069647 0.79
SCHEMBL9052390 0.75
SCHEMBL4612501 0.75
SCHEMBL9261125 0.71
SCHEMBL11565964 0.70
SCHEMBL9257474 0.70 EPHX1 (0.33)
SCHEMBL4059442 0.70
SCHEMBL9255078 0.70
SCHEMBL8996656 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040266864-A1 Methods for treating depression and other CNS disorders using enantiomerically enriched desmethyl-and didesmethyl-metabolites of citalopram SEPRACOR INC. 2004-12-30 US claimed
EP-1446396-A1 METHODS FOR TREATING DEPRESSION AND OTHER CNS DISORDERS USING ENANTIOMERICALLY ENRICHED DESMETHYL- AND DIDESMETHYL-METABOLITES OF CITALOPRAM Sepracor, Inc. (US) 2004-08-18 EP claimed
WO-2003040121-A1 METHODS FOR TREATING DEPRESSION AND OTHER CNS DISORDERS USING ENANTIOMERICALLY ENRICHED DESMETHYL- AND DIDESMETHYL-METABOLITES OF CITALOPRAM SEPRACOR, INC. (US) 2003-05-15 WO claimed
US-6281232-B1 AZABICYCLIC RING-SUBSTITUTED THIA- OR OXADIAZOLES NOVO NORDISK A/S (DK) 2001-08-28 US disclosed
US-6265419-B1 IRRITABLE BOWEL DISORDER NOVO NORDISK A/S (DK) 2001-07-24 US disclosed
CN-1046722-C Heterocyclic compounds and their preparation and use NOVO NORDISK AS (DK) 1999-11-24 CN disclosed
US-5710151-A ADMINISTERING A THIADIAZOLE OR AN OXADIAZOLE DERIVATIVE TO A SUBJECT MUHLHAUSER MARK A (US) 1998-01-20 US disclosed
US-5679686-A TREATING SCHIZOPHRENIA BY ADMINISTERING THIADIAZOLE OR OXADIAZOLE DERIVATIVES NOVO NORDISK A/S (DK) 1997-10-21 US disclosed
US-5677313-A ADMINISTERING 1,2,5-THIADIAZOLYL-AZABICYCLONONENE DERIVATIVES NOVO NORDISK A/S (DK) 1997-10-14 US disclosed
US-5663182-A ADMINISTERING AN AZABICYCLIC RING SUBSTITUTED THIADIAZOLE OR OXADIAZOLE TO A MAMMAL BYMASTER FRANKLIN PORTER (US) 1997-09-02 US disclosed
US-5641791-A USEFUL AS STIMULANTS OF COGNITIVE FUNCTION OF FOREBRAIN AND HIPPOCAMPUS OF MAMMALS AND IN THE TREATMENT OF ALZHIEMER'S DISEASE, SEVERE PAIN AND GLAUCOMA NOVO NORDISK A.S (DK) 1997-06-24 US disclosed
US-5635449-A Arylthioalkyl- and arylthioalkenylphosphonic acids and derivatives thereof useful as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1997-06-03 US disclosed
US-5574043-A ALZHEIMERS, GLAUCOMA, ANALGESIC NOVO NORDISK A/S (DK) 1996-11-12 US disclosed
US-5527813-A THERAPEUTICALLY ACTIVE AZABICYCLIC COMPOUNDS USEFUL AS STIMULANTS OF THE COGNITIVE FUNCTION OF THE FOREBRAIN AND IN THE TREATMENT OF ALZHEIMER'S DISEASE NOVO NORDISK A/S (DK) 1996-06-18 US disclosed
CN-1121349-A Heterocyclic compounds and their preparation and use NOVO NORDISK AS (DK) 1996-04-24 CN disclosed