Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881095 | 0.83 | FOLH1 (0.47) | HRH3GLAFOLH1IDH1MEP1A | |
| SCHEMBL19442376 | 0.82 | GLA (0.56) | HRH3GLAFOLH1SLC6A2SLC6A4 | |
| SCHEMBL28046794 | 0.81 | GLA (0.55) | HRH3GLAFOLH1IDH1MEP1A | |
| SCHEMBL6668208 | 0.80 | HRH3 (0.68) | HRH3IDH1DPP4MAOBLMNA | |
| SCHEMBL34461699 | 0.79 | FOLH1 (0.55) | GLAFOLH1IDH1MEP1AMEP1B | |
| SCHEMBL14462270 | 0.79 | FOLH1 (0.55) | GLAFOLH1IDH1MEP1AMEP1B | |
| SCHEMBL10442382 | 0.79 | FOLH1 (0.49) | GLAFOLH1IDH1MEP1AMEP1B | |
| SCHEMBL30834629 | 0.79 | FOLH1 (0.55) | GLAFOLH1IDH1MEP1AMEP1B | |
| SCHEMBL27307972 | 0.79 | FOLH1 (0.55) | GLAFOLH1IDH1MEP1AMEP1B | |
| SCHEMBL22395447 | 0.78 | FOLH1 (0.50) | HRH3GLAFOLH1IDH1MEP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022568-A1 | ARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-18 | — | — | WO | disclosed |