SCHEMBL6667023

SCHEMBL6667023

CC(C)N(Cc1ccncc1)C(=O)Cc1c(-c2ccc(Br)cc2)[nH]c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 19/20 1.00
FNTB P49356 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671324 0.92 FNTA (1.00) FNTAFNTB
SCHEMBL6669170 0.90 FNTA (0.92) FNTAFNTB
SCHEMBL6668193 0.86 FNTA (0.85) FNTAFNTB
SCHEMBL6667333 0.84 FNTA (1.00) FNTAFNTB
SCHEMBL6672695 0.84 FNTA (0.81) FNTAFNTB
SCHEMBL6666624 0.84 FNTA (0.90) FNTAFNTB
SCHEMBL6664852 0.84 FNTA (0.85) FNTAFNTB
SCHEMBL6680247 0.83 FNTA (1.00) FNTAFNTB
SCHEMBL6680254 0.83 FNTA (1.00) FNTAFNTB
SCHEMBL6668379 0.83 FNTA (1.00) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1324985-A4 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO INC (US) 2004-10-06 EP claimed
EP-1324985-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 2003-07-09 EP claimed
WO-2002028831-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2002-04-11 WO claimed
EP-1324985-A4 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO INC (US) 2004-10-06 EP disclosed
EP-1324985-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 2003-07-09 EP disclosed
WO-2002028831-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2002-04-11 WO disclosed