SCHEMBL6667042

SCHEMBL6667042

CO[C@H]1O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@H](O)[C@H]1OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SSTR1 P30872 1/20 0.58
SSTR2 P30874 1/20 0.58
SSTR4 P31391 1/20 0.58
SSTR3 P32745 1/20 0.58
SSTR5 P35346 1/20 0.58
GJB2 P29033 5/20 0.55
TACR2 P21452 1/20 0.49
PTPN1 P18031 4/20 0.49
PTPN2 P17706 2/20 0.49
NT5E P21589 1/20 0.48
GJA1 P17302 3/20 0.47
CDC25B P30305 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22659920 1.00 SSTR1 (0.58) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL26256369 1.00 SSTR1 (0.58) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL22858228 1.00 SSTR1 (0.58) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL10609599 1.00 SSTR1 (0.58) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL18671703 1.00 SSTR1 (0.58) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL24371601 0.94 SSTR1 (0.57) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL18671860 0.94 SSTR1 (0.57) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL11066790 0.94 SSTR1 (0.57) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL12896366 0.94 SSTR1 (0.57) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL264401 0.94 SSTR1 (0.57) SSTR1SSTR2SSTR4SSTR3SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114514235-A Novel galactoside inhibitors of galectins 格莱克特生物技术公司 2022-05-17 CN disclosed
EP-0901498-B1 METHOD FOR SYNTHESIZING C-GLYCOSIDES OF ULOSONIC ACIDS UNIV IOWA RES FOUND (US) 2004-09-22 EP disclosed
US-6376662-B1 REACTING AN ULOSONIC ACID SULFONE OR PHOSPHITE WITH AN ALDEHYDE OR KETONE COMPOUND IN THE PRESENCE OF A LANTHANIDE METAL HALIDE. UNIVERSITY OF IOWA RESEARCH FOUNDATION 2002-04-23 US disclosed
EP-0901498-A2 METHOD FOR SYNTHESIZING C-GLYCOSIDES OF ULOSONIC ACIDS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1999-03-17 EP disclosed
WO-1998031696-A2 METHOD FOR SYNTHESIZING C-GLYCOSIDES OF ULOSONIC ACIDS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1998-07-23 WO disclosed