Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.67 |
| ▸ | FNTB | P49356 | 14/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667501 | 0.82 | FNTA (0.71) | FNTAFNTB | |
| SCHEMBL6669744 | 0.80 | FNTA (0.74) | FNTAFNTB | |
| SCHEMBL6665854 | 0.80 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6669628 | 0.80 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6667459 | 0.79 | FNTA (0.73) | FNTAFNTB | |
| SCHEMBL6668185 | 0.78 | FNTA (0.70) | FNTAFNTB | |
| SCHEMBL6668364 | 0.78 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6668449 | 0.78 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6668101 | 0.77 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6666294 | 0.77 | FNTA (0.74) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324985-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2004-10-06 | — | — | EP | claimed |
| EP-1324985-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2003-07-09 | — | — | EP | claimed |
| WO-2002028831-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-04-11 | — | — | WO | claimed |
| EP-1324985-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-1324985-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002028831-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-04-11 | — | — | WO | disclosed |