Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 15/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 12/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.42 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.42 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluconazole SCHEMBL6667639 | 0.83 | CYP3A4 (0.69) | CYP3A4CYP2C9CYP2C19LMNAHSP90AA1 | |
| SCHEMBL14222636 | 0.82 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2C19LMNAHSP90AA1 | |
| SCHEMBL2326132 | 0.82 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2C19LMNAHSP90AA1 | |
| SCHEMBL30944259 | 0.82 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2C19LMNAHSP90AA1 | |
| SCHEMBL14222637 | 0.81 | CYP3A4 (0.59) | CYP3A4CYP2C9CYP2C19LMNAHSP90AA1 | |
| SCHEMBL4798487 | 0.80 | CYP3A4 (0.62) | CYP3A4CYP2C9CYP2C19LMNAHSP90AA1 | |
| SCHEMBL4650458 | 0.78 | CYP3A4 (0.55) | CYP3A4CYP2C9CYP2C19LMNAHSP90AA1 | |
| SCHEMBL4800972 | 0.77 | CYP3A4 (0.54) | CYP3A4CYP2C9CYP2C19LMNAHSP90AA1 | |
| SCHEMBL4799200 | 0.75 | CYP3A4 (0.57) | CYP3A4CYP2C9CYP2C19LMNAHSP90AA1 | |
| SCHEMBL4652215 | 0.75 | CYP3A4 (0.56) | CYP3A4CYP2C9CYP2C19LMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453952-A2 | COMPOSITIONS AND METHODS FOR NORMALIZING ASSAYS | Diversa Corporation (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050265-A2 | COMPOSITIONS AND METHODS FOR NORMALIZING ASSAYS | DIVERSA CORPORATION (US) | 2003-06-19 | — | — | WO | disclosed |