Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547932 | 0.87 | MRGPRX4 (0.46) | MRGPRX4TSHRENPP2PRSS1PRSS2 | |
| SCHEMBL29928701 | 0.87 | MRGPRX4 (0.46) | MRGPRX4TSHRENPP2PRSS1PRSS2 | |
| SCHEMBL123838 | 0.84 | TSHR (0.61) | MRGPRX4TSHRENPP2PRSS1PRSS2 | |
| SCHEMBL6782118 | 0.84 | MRGPRX4 (0.44) | MRGPRX4TSHRENPP2PRSS1PRSS2 | |
| SCHEMBL21778883 | 0.84 | MRGPRX4 (0.50) | MRGPRX4TSHRENPP2PRSS1PRSS2 | |
| SCHEMBL29442637 | 0.84 | TDP1 (0.48) | MRGPRX4TSHRSMN1; SMN2NPC1TP53 | |
| SCHEMBL12951814 | 0.84 | TDP1 (0.48) | MRGPRX4TSHRSMN1; SMN2NPC1TP53 | |
| SCHEMBL13301373 | 0.82 | MRGPRX4 (0.43) | MRGPRX4TSHRENPP2PRSS1PRSS2 | |
| SCHEMBL13301460 | 0.82 | MRGPRX4 (0.43) | MRGPRX4TSHRENPP2PRSS1PRSS2 | |
| SCHEMBL21533306 | 0.82 | SMN1; SMN2 (0.68) | MRGPRX4TSHRSMN1; SMN2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004621-B1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN CHEMICALS LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6485657-B1 | Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer | TEIJIN, LIMITED (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |